Augmenting tendon and ligament repair with platelet-rich plasma (PRP)

Augmenting tendon and ligament repair with platelet-rich plasma (PRP).

Tendon and ligament injuries (TLI) commonly occur in athletes and non-athletes alike, and remarkably debilitate patients' athletic and personal abilities. Current clinical treatments, such as reconstruction surgeries, do not adequately heal these injuries and often result in the formation of scar tissue that is prone to re-injury. Platelet-rich plasma (PRP) is a widely used alternative option t...

Tissue Engineering: Oromaxillofacial reconstruction with platelet rich plasma (PRP)

Autologous Platelet Rich Plasma Injection Improves Early Tendon Repair in Rabbits: A Histopathological and Biomechanical Study

Objective- The aim of this study was to investigate the PRP effects on the early time-period during tendon healing in rabbits DDF tendon. Design-Experimental study Animals- Twenty male New Zealand white rabbits Procedure-PRP samples were prepared using twice centrifugation method of modification of the Cuarsan...

Platelet Rich Plasma ( PRP ) Therapy

Molloy, et. al., (2003) address specific growth factors encountered in ligament and tendon healing. After reading about the factors found in superficial wounds, above, these should appear familiar, including: Platelet derived growth factor (PDGF)—produced shortly after tendon injury, stimulates production of other growth factors such as IGF-1, and is involved in the tissue remodeling phase of h...

Efficacy of Autologous Platelet-Rich Plasma (PRP) Activated By Thromboplastin-D on the Repair and Regeneration of Wounds in Dogs

Objective- To evaluate the effects of autologous platelet-rich plasma (PRP) on wound healing in dogs. Design- Experimental in-vivo study. Animals- 5 mix-breed male adult dogs. Procedures- Under general anesthesia, six 2 × 2-cm, full-thickness skin wounds were created on the back of dogs symmetrically. In each dog, three right side wounds were treated topically with 1.5 ml PRP jelly, whereas lef...